CLINICAL OBSERVATIONS & DERMATOLOGICAL DATA

One treatment.
Results that last.

The changes observed with Exovelle did not fade on treatment day. They were photographed under standardized clinical lighting and measured using computerized ImageJ topography analysis three weeks post-application.

EXOSOMES
19 studies

A 2026 systematic review of human clinical trials confirmed significant gains in hydration, elasticity, fine lines, pore refinement, and dermal tolerance.

GROWTH FACTORS
+37% collagen

Topical application of physiological growth factor complexes expanded the grenz zone of newly synthesized collagen fibers directly below the epidermis.

FIRMING PEPTIDES
-55.8% wrinkles

In a double-blind trial of women aged 40 to 65, copper peptide complexes reduced wrinkle volume by 55.8% and depth by 32.8% versus placebo over 8 weeks.

HYDRATION SURGE
+134% hydration

Multi-fractional hyaluronic matrices spiked stratum corneum moisture levels by 134% immediately, maintaining a 55% elevation at 6 weeks.

MEASURED WITH IMAGEJ ANALYSIS

Single 1.5 mL Session • 3-Week Trajectory

Subjects received one professional stamping treatment with Exovelle without additional adjuvant therapies. Below are the verified photographic outcomes.

Case 1 • Single Treatment ImageJ Verified

Woman, Late Seventies

-21% Wrinkles & Texture

Three weeks after a single 1.5 mL treatment, computerized ImageJ image analysis measured a 21% reduction in wrinkle volume and furrow depth. Visible resolution of micro-vascular redness and chronic erythema was recorded, yielding a calmer, rejuvenated complexion.

Patient Satisfaction 83% Highly Satisfied
Downtime < 8 Hours Transient
Display Format:
A • Before Case 1 Woman Late 70s Before Treatment
B • 3 Weeks After Case 1 Woman Late 70s 3 Weeks After
Photographs published with written consent; eyes shielded to protect patient privacy.
Case 2 • Single Treatment ImageJ Verified

Woman, Mid-Fifties

+18% Firmness & Elasticity

Three weeks after one treatment, skin showed marked increases in surface luminescence, dermal turgor, and rosy tone. Computerized ImageJ density evaluation documented an 18% improvement in structural skin firmness, with 100% visible improvement noted by evaluating physicians.

Elasticity Gain +18% Measured
Luminance 100% Visible Lift
Display Format:
A • Before Case 2 Woman Mid 50s Before Treatment
B • 3 Weeks After Case 2 Woman Mid 50s 3 Weeks After
Photographs published with written consent; eyes shielded to protect patient privacy.
THE SPLIT-FACE COMPARISON

One Face. Two Sides. A Clear Difference.

The most unassailable methodology in aesthetic science: treat one hemi-facial plane with Exovelle while leaving the other untouched. Same patient, same genetics, same ambient lighting.

Split Face Woman Case 3 Full Face

Lift: Case 3 • Woman, Early 50s

3 Weeks

Treated on left side of photograph: The treated side displays a visibly elevated malar fat pad, more sculpted mandibular jawline contour, and smoothed periorbital/under-eye transition.

High-Magnification Periorbital Close-Up Under-eye and Cheek Magnification Woman Case 3
TREATED SIDE UNTREATED SIDE
Split Face Man Case 4 Full Face

Fullness: Case 4 • Man, Mid-50s

Post Treatment

Treated on right side of photograph: The treated side demonstrates visibly replenished structural fullness in the cheek and sub-orbital trough with a smoother, thicker skin barrier, establishing universal efficacy across male skin physiology.

High-Magnification Periorbital Close-Up Under-eye and Cheek Magnification Man Case 4
UNTREATED SIDE TREATED SIDE
Photographs published with written consent; eyes covered to protect subject identity. Dashed midline marks facial dividing plane.
DATA TABLE

Summary of Clinical Observations

Four representative patient cohorts monitored under clinical oversight:

Case Client Cohort Clinical Protocol & Design Follow-up Documented Outcome
1 Woman, late seventies Before & after, single 1.5 mL stamping treatment 3 weeks 21% wrinkle reduction (ImageJ analysis); visibly calmer erythema & even complexion
2 Woman, mid-fifties Before & after, single 1.5 mL stamping treatment 3 weeks 18% firmness improvement (ImageJ analysis); visibly brighter, rosier, and firmer tone
3 Woman, early fifties Split-face: treated vs. untreated contralateral side 3 weeks Visible lift on treated side; higher cheek contour, refined under-eye texture
4 Man, mid-fifties Split-face: treated vs. untreated contralateral side Post-treatment Visible fullness on treated side; plumper, smoother male dermal architecture
Published studies describe the foundational science behind each technology. Results shown are from individual clinical cases. Exovelle is a professional cosmetic serum.